The laboratory has been studying the association of the orbital frontal cortex (OFC) to aggression and impulsivity. Click to see images of the tissue segmented brain in which the gray matter of the OFC has been traced on anterior, mid, and posterior slices. Click here to see images of the tissue segmented brain in which the gray matter of the DLPFC has been traced on anterior, mid, and posterior planes.

In a project on divergent thinking white matter thresholding and two-dimensional segmentation of the corpus callosum were used. Recently, Dr. Jerram has been mentoring students in the use of voxel-based morphometry (VBM) in SPM2. VBM is a whole-brain unbiased technique for analyzing structural MRI data and comparing groups using parametric statistical methods. Click here to see image files of brains processed in VBM: tissue segmentation output of a single subject, normalization of a single subject to a customized template (the upper left image is the single subject raw image, the center image is the customized template, and the lower right image is the single subject warped image), and statistical parametric map of a contrast of group of 10 SPGR images vs. 10 MPRAGE images of heterogeneous psychiatric patient samples matched on age, education and WRAT-Reading scores.

Dr. Jerram has also recently begun using intraclass correlation methods in functional MRI data to examine reliability of fMRI data and will continue to incorporate other statistical techniques to expand the types of questions that can be asked of structural and functional MRI data.